Of Mice and Men (1981)

George and Lenny travel through the Depression-era west working at odd jobs, hoping to make enough money to buy their own farm. George must always watch over his intellectually disabled friend, and keep him out of danger, both to himself and to others. After they take a new job at a ranch, Lenny gets into far more trouble than George can talk his way out of, leaving George to decide whether to help him, or leave him to his fate.